刘培

发布者:花文婷发布时间:2022-09-27浏览次数:12

职称:副教授       E-mail:liupei@njucm.edu.cn      主要研究方向:中药资源化学与方剂功效物质基础研究


 

个人简介

副教授,医学科学博士。主要研究方向为中药资源化学与方剂功效物质基础研究,具体包括:(1)经典名方及其组方药对、药味的功效物质基础及配伍规律研究;(2)道地药材品质形成机制研究。入选江苏省六大人才高峰高层次人才培养对象、江苏省高校青蓝工程优秀青年骨干教师培养对象。主持国家自然科学基金、江苏省自然科学基金优秀青年基金、江苏省高校重大基础研究计划等科研项目近10项。作为主要贡献者获教育部自然科学一等奖、中华中医药学会科学技术一等奖、农业农村部2016-2018年度全国农牧渔业丰收奖二等奖。以第一或通讯作者发表高水平学术论文30余篇。第一发明人获授权发明专利4项。参编专著4部,副主编学术专著2部。

 

承担的主要科研项目

1、国家自然科学基金面上项目,81573555,基于药物相互作用的香附气血药对相使和合的组成结构与协同增效机理研究,2016/01-2019/1272万元,已结题,主持

2、江苏省基础研究计划(自然科学基金)优秀青年基金项目,BK20160097,香附四物汤干预气滞血瘀型痛经的代谢组学研究,2016/7-2019/650万元,已结题,主持

3、国家自然科学基金青年基金,8120288,香附四物汤干预气滞血瘀证原发性痛经的功效物质基础研究,2013/01-2015/1222万元,已结题,主持

4、江苏省自然科学青年科学基金,BK2012456,香附四物汤干预气滞血瘀证原发性痛经的代谢组学研究,2012/07-2015/0620万元,已结题,主持

5、江苏省自然科学基金面上项目,BK20201403,栝楼果瓤传统功效的物质基础与作用机制研究,2020/07-2023/0610万元,在研,主持

 

代表性论文

[1] Xin Pan, Pei Liu*, Yi-Wei Wang, Yan-Ling Yi, Huang-Qin Zhang, Da-Wei Qian, Ping Xiao, Er-Xin Shang, Jin-Ao Duan*. Synthesis of starch nanoparticles with controlled morphology and various adsorption rate for urea. Food Chemistry, 2022, 369: 130882

[2] Shao-Qing Zhu, Pei Liu*, Wen-Xing Wu, Dan Li, Er-Xin Shang, Sheng Guo, Da-Wei Qian, Hui Yan, Wei Wang, Jin-Ao Duan*. Multi-constituents variation in medicinal crops processing: Investigation of nine cycles of steam-sun drying as the processing method for the rhizome of Polygonatum cyrtonema. Journal of Pharmaceutical and Biomedical Analysis, 2021, 209: 114497

[3] Wei-Meng Feng†, Pei Liu†, Hui Yan*, Sen Zhang, Er-Xin Shang, Guang Yu, Shu Jiang, Da-Wei Qian, Jun-Wei Ma and Jin-Ao Duan*. Impact of Bacillus on Phthalides Accumulation in Angelica sinensis (Oliv.) by Stoichiometry and Microbial Diversity Analysis. Frontiers in Microbiology, 2021, 11: 611143.

[4] Hui-wei Li#, Pei Liu#, Huang-qin Zhang, Wei-meng Feng, Hui Yan, Sheng Guo, Da-wei Qian, Jin-ao Duan*. Determination of bioactive compounds in the nonmedicinal parts of Scrophularia ningpoensis using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry and chemometric analysis. Journal of Separation Science, 2020, 43(22): 4191-4201.

[5] Huang-qin Zhang, Pei Liu*, Jin-ao Duan*, Ling Dong, Er-xin Shang, Da-wei Qian, Zhen-hua Zhu, Hui-wei Li, Wei-wen Li. Comparative analysis of carbohydrates, nucleosides and amino acids in different parts of Trichosanthes kirilowii Maxim. by (ultra) high-performance liquid chromatography coupled with tandem mass spectrometry and evaporative light scattering detector methods. Molecules, 2019, 24, 1440.

[6] Huang-qin Zhang, Pei Liu*, Jin-ao Duan*, Ling Dong, Er-Xin Shang, Da-wei Qian, Ping Xiao, Ming Zhao, Wei-wen Li. Hierarchical extraction and simultaneous determination of flavones and triterpenes in different parts of Trichosanthes kirilowii Maxim. by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2019, 167: 114-122.

[7] Pei Liu*, Er-xin Shang, Yue Zhu, Da-wei Qian, Jin-ao Duan*. Volatile component interaction effects on compatibility of Cyperi Rhizoma and Angelicae Sinensis Radix or Chuanxiong Rhizoma by UPLC-MS/MS and response surface analysis. Journal of Pharmaceutical and Biomedical Analysis, 2018, 160: 135-143.

[8] Pei Liu, Er-Xin Shang, Yue Zhu, Jin-Gao Yu, Da-Wei Qian, Jin-Ao Duan*. Comparative analysis of compatibility effects on invigorating blood circulation for Cyperi Rhizoma series of herb pairs using untargeted metabolomics. frontiers in Pharmacology, 2017, 8: article 677.

[9] Pei Liu, Yuan Xu, Hui Yan, Jing Chen, Er-Xin Shang, Da-Wei Qian, Shu Jiang, Jin-Ao Duan*. Characterization of molecular signature of the roots of Paeonia lactiflora during growth. Chinese Journal of Natural Medicines, 2017, 15(10):0785-0793

[10] Pei Liu, Jin-long Zhao, Jin-ao Duan*, Da-wei Qian, Sheng Guo, Yu-ping Tang. Assay of 44 compounds in the cortex and xylem from roots and branches of Ginkgo biloba L. by ultra high performance liquid chromatography coupled with tandem mass spectrometry and chemometric analysis. Journal of Separation Science, 2015, 38: 3815-3824.

 

获得奖项与荣誉

刘培(1/3),栝楼资源的综合利用,第七届江苏省“互联网+”大学生创新创业大赛三等奖,指导老师,2021

刘培(1/2),栝楼资源循环利用的实践,首届江苏省研究生“健康江苏”创意大赛,优秀指导老师,2018

刘培(8/25),栝楼绿色高效生产关键技术研究与示范推广,农业农村部2016-2018年度全国农牧渔业丰收奖(农业技术推广成果奖)二等奖2019

刘培(8/15),代表性经典方剂类方衍化关系与功效物质研究技术体系创建及其应用,中华中医药学会,科学技术奖,一等奖,2016

刘培(3/16),四物汤类方治疗不同证型原发性痛经的功效物质基础与生物学机制,国家教育部,自然科学奖,一等奖,2015




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